Neuroscanning resolution continues to increase

>> Monday, August 31, 2009

ScienceDaily - August 30, 2009

In this image, neurons fired by electrical stimulation are seen in bright red. (Credit: Image courtesy of Harvard Medical School)

For over a century, scientists have been using electrical stimulation to explore and treat the human brain. The technique has helped identify regions responsible for specific neural functions—for instance, the motor cortex and pleasure center—and has been used to treat a variety of conditions from Parkinson's disease to depression. Yet no one has been able to see what actually happens at the cellular level when the brain is electrically prodded.

Now, with the aid of optical imaging technology, researchers in the lab of HMS neurobiology professor Clay Reid have taken the first look at this process. They found that the neural response to electrical currents isn't localized, as some had previously thought. That is, not all neurons immediately surrounding an electrode fire when a charge is delivered. Rather, a scattered and widely distributed set of neurons switch on. These findings, which will appear in the August 27 issue of Neuron, promise to end a longstanding debate about how neurons react to electrical stimulation.

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Imaging a single molecule - a tiny leap forward for nanotech

>> Sunday, August 30, 2009

Mail Online - August 28, 2009, by Clair Bates

The delicate inner structure of a pentacene molecule has been imaged with an atomic force microscope

It may look like a piece of honeycomb, but this lattice-shaped image is the first ever close-up view of a single molecule.

Scientists from IBM used an atomic force microscope (AFM) to reveal the chemical bonds within a molecule.

'This is the first time that all the atoms in a molecule have been imaged,' lead researcher Leo Gross said.

The researchers focused on a single molecule of pentacene, which is commonly used in solar cells. The rectangular-shaped organic molecule is made up of 22 carbon atoms and 14 hydrogen atoms.

In the image above the hexagonal shapes of the five carbon rings are clear and even the positions of the hydrogen atoms around the carbon rings can be seen.

To give some perspective, the space between the carbon rings is only 0.14 nanometers across, which is roughly one million times smaller than the diameter of a grain of sand.

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Augmented reality apps hit iPhone

NYT - August 27, 2009, by Marshall Kirkpatrick

First Paris Metro, then Yelp, now London Buses. The newest is even selling database layers through in-app purchase.

It's been widely reported that the API required to display Augmented Reality (AR) layers of data on top of the camera view of a non-jailbroken iPhone 3Gs would not be publicly exposed until the launch of the next version of the iPhone Operating System, expected this Fall. Many developers are patiently waiting, but some have now found a way around the restriction. We just received word of the 3rd AR-enabled app hitting the iTunes store.

Earlier this week we reported on Paris Metro Subway as apparently the first AR-enabled app to be accepted into iTunes. Then, this afternoon Robert Scoble discovered that the new Yelp app includes an AR easter egg that any 3Gs owner can turn on by shaking their phone. Now we've received an email from Presselite, the same company that made Paris Metro Subway, letting us know that its London Bus app has been updated to include AR overlays and is also live in the App Store.

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Quantum secrets soon available for the masses

>> Friday, August 28, 2009

Technology Review - August 28, 2009, by Duncan Graham-Rowe

Light box: id Quantique's Cerberis quantum key distribution system (bottom) with two link encryption units (above) is now widely available over dark fiber networks. Credit: id Quantique.

A new partnership will make quantum cryptography more widely available.

Quantum cryptography could finally hit the mainstream thanks to a deal that will allow customers to adopt the technology without having to install dedicated optical fibers.

Quantum cryptography--a means of keeping secrets safe by using light particles to help scramble data--has been commercially available for several years. But the technology has only been practical for governmental or large private-sector organizations that can afford to have their own point-to-point optical fiber that the technology requires. But under the new deal, struck between Siemens IT Solutions and Services in the Netherlands and Geneva, Switzerland-based id Quantique, any organizations or individuals wanting state-of-the-art data security will be able to buy the complete package of quantum cryptography and cable.

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It's not flying cars, but it's close

>> Thursday, August 27, 2009

Science Daily - August 27, 2009

European researchers have developed new control systems that let driverless vehicles communicate and cooperate with each other. Could fleets of high throughput rapid transit systems soon be cruising our cities?

Many metro and tram systems effectively run automatically nowadays. Still, it is reassuring to see the driver in the cab, knowing someone is there to take over in an emergency or to override the computer's controls if necessary. But European researchers in the CyberCars2 project (http://www-c.inria.fr/cybercars2) have now demonstrated that vehicles can be left to themselves much more. If allowed to 'talk' to each other, automated vehicles can organise themselves well enough to get around efficiently and safely.

Two earlier EU-funded projects, CyberCars and CyberMove, developed the sense and control systems by which unmanned road-based vehicles, called cybercars, could safely navigate the streets.

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Taking chickens back to their dinosaur roots

>> Wednesday, August 26, 2009

PhysOrg.com - August 25, 2009

After years spent hunting for the buried remains of prehistoric animals, a Canadian paleontologist now plans to manipulate chicken embryos to show he can create a dinosaur.

Hans Larsson, the Canada Research Chair in Macro Evolution at Montreal's McGill University, said he aims to develop dinosaur traits that disappeared millions of years ago in birds.

Larsson believes by flipping certain genetic levers during a chicken embryo's development, he can reproduce the dinosaur anatomy, he told AFP in an interview.

Though still in its infancy, the research could eventually lead to hatching live prehistoric animals, but Larsson said there are no plans for that now, for ethical and practical reasons -- a dinosaur hatchery is "too large an enterprise."

"It's a demonstration of evolution," said Larsson, who has studied bird evolution for the last 10 years.

"If I can demonstrate clearly that the potential for dinosaur anatomical development exists in birds, then it again proves that birds are direct descendants of dinosaurs."

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Robot bones

>> Tuesday, August 25, 2009

New Scientist - August 24, 2009



YOU may have more in common with this robot than any other - it was designed using your anatomy as a blueprint.

Conventional humanoid robots may look human, but the workings under their synthetic skins are radically different from our anatomy. A team with members across five European countries says this makes it difficult to build robots able to move like we do.

Their project, the Eccerobot, has been designed to duplicate the way human bones, muscles and tendons work and are linked together. The plastic bones copy biological shapes and are moved by kite-line that is tough like tendons, while elastic cords mimic the bounce of muscle.

Mimicking human anatomy is no shortcut to success, though, as even simple human actions like raising an arm involve a complex series of movements from many of the robot's bones, muscles and tendons. However, the team is convinced that solving these problems will enable the construction of a machine that interacts with its environment in a more human manner.

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If you thought robotic hands were clumsy and slow...think again.

>> Monday, August 24, 2009

Hizook - August 3, 2009 by Travis Deyle



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Artificial life only months away

>> Saturday, August 22, 2009

Mail Online - August 22, 2009

Scientists are only months away from  creating artificial life, it was claimed yesterday.

Dr Craig Venter – one of the world’s most famous and controversial biologists – said his U.S. researchers have overcome one of the last big hurdles to making a synthetic organism.

The first artificial lifeform is likely to be a simple man-made bacterium that proves that the technology can work.

But it will be followed by more complex bacteria that turn coal into cleaner natural gas, or algae that can soak up carbon dioxide and convert it into fuels.

They could also be used to create new vaccines and antibiotics.

The prediction came after a breakthrough by the J Craig Venter Institute in Maryland.

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Finally, true life-extension drugs to be tested

>> Friday, August 21, 2009

NYT - August 17, 2009, by Nicholas Wade

It may be the ultimate free lunch — how to reap all the advantages of a calorically restricted diet, including freedom from disease and an extended healthy life span, without eating one fewer calorie. Just take a drug that tricks the body into thinking it’s on such a diet.

It sounds too good to be true, and maybe it is. Yet such drugs are now in clinical trials. Even if they should fail, as most candidate drugs do, their development represents a new optimism among research biologists that aging is not immutable, that the body has resources that can be mobilized into resisting disease and averting the adversities of old age.

This optimism, however, is not fully shared. Evolutionary biologists, the experts on the theory of aging, have strong reasons to suppose that human life span cannot be altered in any quick and easy way. But they have been confounded by experiments with small laboratory animals, like roundworms, fruit flies and mice. In all these species, the change of single genes has brought noticeable increases in life span.

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An immune system for the Internet

>> Tuesday, August 18, 2009

Editor's Note: The human body has an immune system developed and refined over billions of years of evolution. It can be defeated, yes,but it saves us from countless attacks every day. Why not a sophisticated immune system for the Internet? Researchers are at work on just such a system.

New Scientist - August 18, 2009, by Anil Ananthaswamy

ISPs may opt to spend their money on other measures - such as speeding up the installation of software patches to plug security holes, notes Baldwin. Or they may have other security priorities, as hackers shift to more covert activities aimed at pilfering money from unsuspecting web users. Nevertheless, worms remain a threat, especially if levels of cyber warfare, such as the targeting of government sites, increase. "Then you might start to see worms [again] and that becomes more important to deal with," says Baldwin.

And if ISPs can be persuaded to cooperate in boosting the internet's immune system, the strategy could also tackle spam - which, at any given time, is the work of a small set of computers spewing out junk email.

"[About] 60 per cent of internet email traffic is spam at the moment," says Coull. "A similar warning and filtering system could actually stop most of the spam from even traversing through the internet."

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Explosion of military robots coming to a war near you

>> Sunday, August 16, 2009

Editor's Note: It's not hard to see why the military loves the idea of robots. Wars are lost by the public's unwillingness to sacrifice the lives of its sons and daughters to far off conflicts that have little obvious bearing on their own lives. So the Pentagon is always looking for ways to wage wars that don't shed blood in copious amounts. Robots don't bleed, and when they are blown up, no one cries (except maybe their creators, but that's a different story). So we can easily understand the motive. What we wonder, though, is how long before Skynet takes over?

PhysOrg.com - August 13, 2009, by Dan De Luce

A prototype of the X-47B Navy Unmanned Combat Air System (UCAS) sits on display at Naval Air Station Pax River Webster Field Annex in St. Inigoes, Maryland, on August 10. The X-47B, made by Northrop Grumman Corporation, is to demonstrate the first-ever carrier-based autonomous launches and recoveries.

Robots in the sky and on the ground are transforming warfare, and the US military is rushing to recruit the new warriors that never sleep and never bleed.

The latest robotics were on display at an industry show this week at a naval airfield in Maryland, with a pilotless helicopter buzzing overhead and a "Wall-E" look-alike robot on the ground craning its neck to peer into a window.

The chopper, the MQ-8B Fire Scout, is no tentative experiment and later this year will be operating from a naval frigate, the USS McInerney, to help track drug traffickers in the eastern Pacific Ocean, Navy officers said.

The rugged little robot searching an enemy building is called a Pakbot, which can climb over rocks with tank treads, pick up an explosive with its mechanical arm and dismantle it while a soldier directs the machine from a safe distance.

There are already 2,500 of them on the ground in Iraq and Afghanistan, and a lighter version weighing six kilograms (14 pounds) has arrived that can be carried in a backpack, according to iRobot, the same company that sells a robot vaccum to civilians, the Roomba.

Monday's demonstration of robotic wonders was organized by defense contractors and the US Navy, which says it wants to lead the American military into a new age where tedious or high-risk jobs are handed over to robots.

"I think we're at the beginning of an unmanned revolution," Gary Kessler, who oversees unmanned aviation programs for the US Navy and Marines, told AFP.

"We're spending billions of dollars on unmanned systems."

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Nick Bostrom - What lies ahead for mankind?

>> Saturday, August 15, 2009

Editor's Note: Nick Bostrom is the Director of the Future of Humanity Institute at Oxford University. In this brief presentation he outlines some possible futures for humanity. I like how he begins, showing a painting depicting the fall of Icharus into the sea while farmers on the shore carry on with their normal activities, oblivious to the dramatic event taking place nearby.



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SD Card lovers, rejoice! 64-gigabytes and more on the way

>> Friday, August 14, 2009

Editor's Note: We take so much for granted, not the least of which is the burgeoning amount of digital storage at our disposal on tiny slivers of silicon. Just a bit of historical perspective might set us straight and allow our jaws to drop in wonder. Hard drive capacity timeline.

NYT - August 13, 2009, by Rick Fairlie

Good news for all you memory hogs out there: Toshiba has announced the world’s largest SD memory card, a 64-gigabyte card that employs the new SDXC (XC for extended capacity) memory standard. The bad news? Your existing digital camera or camcorder won’t read the card format out of the box.

More bad news: The high-capacity memory card won’t hit the store shelves until next spring.

Toshiba said the new SDXC format would support memory card capacities of up to a whopping 2 terabytes. Pricing for the 64-gigabyte card will depend on market prices for flash memory in the spring, according to the company.

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What we can't see can kill us. We need bigger telescopes!

>> Thursday, August 13, 2009

Editor's Note: We're keeping an eye out for asteroids that can wipe out most of Earth's extant species. Good. But a special panel tells us that smaller (less than 1 km across) asteroids, which we're not able to spot with the currently assigned telescopes, if they strike us, won't be a picnic either.

New Scientist - August 12, 2009, by David Shiga

Asteroid Eros, seen here by NASA's NEAR spacecraft, is 33 kilometres wide, making it the second largest near-Earth asteroid (Image: NEAR Project/NLR/JHUAPL/Goddard SVS/NASA)

Existing sky surveys miss many asteroids smaller than 1 kilometre across, leaving the door open to damaging impacts on Earth with little or no warning, a panel of scientists reports. Doing better will require devoting more powerful telescopes to asteroid hunting, but no one has committed the funds needed to do so, it says.

Near-Earth asteroids larger than 1 kilometre across could blast huge amounts of sunlight-blocking dust into Earth's atmosphere in an impact, causing devastating climate change. The US Congress asked NASA in 1998 to find 90 per cent of those in this size range within 10 years, a goal that has now nearly been reached.

Astronomers have now found 784 of them, mostly using telescopes funded by NASA. That works out to 83 per cent of the 940 estimated to be out there by astronomer Alan Harris of the Space Science Institute in Boulder, Colorado.

But asteroids below 1 kilometre in size can cause serious harm, too, and they hit Earth more frequently because they are more numerous. To address the small-asteroid threat, Congress told NASA in 2005 to find 90 per cent of the near-Earth asteroids larger than 140 metres across by 2020.

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Augmented Reality to arrive on cell phones

>> Wednesday, August 12, 2009

Editor's Note: Baby steps, to be sure. Enhanced vision will reach its ultimate stage when data is fed directly into the visual centers of our brains but, for now, it's nice to see us moving in the right direction. For cell phone makers though, this is the next killer app.

BBC News - August 11, 2009, by Michael Fitzpatrick



It's a gift that was once the preserve of fictional cyborgs.

Call it Terminator Vision - a view of the world tagged with rich, location-relevant information whilst your gaze flickers here and there.

But now this Augmented Reality (AR), as it is known, is materialising in the real world.

Mobile phone operators, at least, are hoping it will be the next big thing as programmers learn to corral all the bells and whistles of smart phones - GPS, video, accelerometers - into "killer applications".

For the first time such AR is available for handsets.

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Wi-Fi Pacemakers - so your doc can monitor you 24/7

>> Tuesday, August 11, 2009

Editor's Note: The pacemaker, albeit a very important little implant, is only one of manyu on an ever-increasing list. Now it can communicate its and its hosts statuses to the Interweb. What does this capability portend? Convenience and health, surely. Control of humanity by an artillect? We will see.

NYT - August 10, 2009, by Reuters

After relying on a pacemaker for 20 years, Carol Kasyjanski has become the first American recipient of a wireless pacemaker that allows her doctor to monitor her health from afar -- over the Internet.

When Kasyjanski heads to St. Francis Hospital in Roslyn, New York, for a routine check-up, about 90 percent of the work has already been done because her doctor logged into his computer and learned most of what he needed to know about his patient.

Three weeks ago Kasyjanski, 61, became the first person in the United States to be implanted with a pacemaker with a wireless home monitoring system that transmits critical information to her doctor via the Internet.

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Tackling complex emerging threats by augmenting our intelligence

>> Monday, August 10, 2009

Editor's Note: When humanity was threatened with extinction some 74,000 years ago by the eruption of a volcano 1,000 times more powerful than Mt. St. Helens, we survived by getting smarter. Today's existential threats are far more complex, and we need lots more brain power to cope. According to this article, we're developing it even as we speak.

The Atlantic Online - July/August 2009, by Jamais Cascio

Seventy-four thousand years ago, humanity nearly went extinct. A super-volcano at what’s now Lake Toba, in Sumatra, erupted with a strength more than a thousand times that of Mount St. Helens in 1980. Some 800 cubic kilometers of ash filled the skies of the Northern Hemisphere, lowering global temperatures and pushing a climate already on the verge of an ice age over the edge. Some scientists speculate that as the Earth went into a deep freeze, the population of Homo sapiens may have dropped to as low as a few thousand families.

The Mount Toba incident, although unprecedented in magnitude, was part of a broad pattern. For a period of 2 million years, ending with the last ice age around 10,000 B.C., the Earth experienced a series of convulsive glacial events. This rapid-fire climate change meant that humans couldn’t rely on consistent patterns to know which animals to hunt, which plants to gather, or even which predators might be waiting around the corner.

How did we cope? By getting smarter. The neuro­physi­ol­ogist William Calvin argues persuasively that modern human cognition—including sophisticated language and the capacity to plan ahead—evolved in response to the demands of this long age of turbulence. According to Calvin, the reason we survived is that our brains changed to meet the challenge: we transformed the ability to target a moving animal with a thrown rock into a capability for foresight and long-term planning. In the process, we may have developed syntax and formal structure from our simple language.

Our present century may not be quite as perilous for the human race as an ice age in the aftermath of a super-volcano eruption, but the next few decades will pose enormous hurdles that go beyond the climate crisis. The end of the fossil-fuel era, the fragility of the global food web, growing population density, and the spread of pandemics, as well as the emergence of radically transformative bio- and nano­technologies—each of these threatens us with broad disruption or even devastation. And as good as our brains have become at planning ahead, we’re still biased toward looking for near-term, simple threats. Subtle, long-term risks, particularly those involving complex, global processes, remain devilishly hard for us to manage.

But here’s an optimistic scenario for you: if the next several decades are as bad as some of us fear they could be, we can respond, and survive, the way our species has done time and again: by getting smarter. But this time, we don’t have to rely solely on natural evolutionary processes to boost our intelligence. We can do it ourselves.

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Large Hadron Collider to restart in November (and destroy the universe?)

>> Sunday, August 09, 2009

Editor's Note: The LHC is gearing up for ignition after a failed attempt (it worked for only 9 days and smashed no atoms). The so-called secrets of the universe are ready to bare themselves. But maybe they don't want to be bared. Maybe the universe will not allow the LHC to operate properly because its successful operation would destroy everything. We'll find out soon enough. Or perhaps the mystery will continue.

MSNBC - August 7, 2009, by Alexander G. Higgins

GENEVA - When launched to great fanfare nearly a year ago, some feared the Large Hadron Collider would create a black hole that would destroy the world. The world's largest scientific machine, built at a cost of $10 billion, has worked only nine days and has yet to smash an atom.

The European Organization for Nuclear Research, known as CERN, said Friday it would restart the collider in November at half power under pressure from scientists eager to conduct experiments to unlock secrets of the universe.

But spokesman James Gillies told The Associated Press they would have to shut down yet again next year to finish repairs so that the Large Hadron Collider can operate at full energy of 7 trillion electron volts — seven times higher than any other machine in the world.

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Using DNA to build tiny mechanical parts

>> Saturday, August 08, 2009

Editor's Note: Unfortunately we can't shrink our submarines down to fit into the recesses of our bodies. We have to build the parts and assemble them in nanoscale. That's quite difficult, but researchers are finding ways to do it, as described in this fascinating article.

NYT - August 6, 2009, by Henry Fountain

A 12-tooth gear, about one-tenth of a micrometer in diameter, assembled from strands of DNA.

You can’t build a machine without parts. That’s true for large machines like engines and pumps, and it’s true for the tiniest machines, the kind that scientists want to build on the scale of molecules to do work inside the body.

Researchers at the Dana-Farber Cancer Institute and Harvard University have taken a step toward creating parts for molecular machines, out of DNA. In a paper in Science, Hendrik Dietz (who is now with the Technical University of Munich), Shawn M. Douglas and William H. Shih describe a programmable technique for twisting and curving DNA into shapes.

Dr. Shih said the method used strands of DNA that self-assemble into rigid bundles, with the individual double helixes joined by strong crosslinks. Manipulating the base pairs in the helixes — using more or fewer of them between crosslinks — creates torque that causes the bundles to twist and bend in a specific direction. The researchers were able to control the degree of bending, and were even able to make a bundle bend back on itself.

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Can you feel it? Touchable Holography

>> Friday, August 07, 2009

Editor's Note: Admittedly, these technologies pale beside the holy grail of full-immersion virtual reality. But they are interesting nonetheless.

PhysOrg.com - August 6, 2009, by Lisa Zyga

Researchers from the University of Tokyo have developed 3D holograms that can be touched with bare hands. Generally, holograms can't be felt because they're made only of light. But the new technology adds tactile feedback to holograms hovering in 3D space.



Called the Airborne Ultrasound Tactile Display, the hologram projector uses an ultrasound phenomenon called acoustic radiation pressure to create a pressure sensation on a user's hands, which are tracked with two Nintendo Wiimotes. As the researchers explain, the method doesn't use any direct contact and so doesn't dilute the quality of the hologram. The researchers, led by Hiroyuki Shinoda, currently have the technology on display at SIGGRAPH 2009 in New Orleans.

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Instant repairs of injuries on the battlefield

>> Thursday, August 06, 2009

Editor's Note: Yesterday's post was about advances being brought about by the needs of scientists. Today its the needs of the military.

Wired - August 3, 2009, by Katie Drummond

The military wants soldiers who can withstand anything - even the worst and most debilitating wartime injuries. Now Darpa, the Pentagon’s far-out research team, is trying to make traumatic injuries more like minor scrapes, patched up to be good as new. Or better.

Darpa’s been working on superhuman soldiers for years. They’ve toyed with cellular mitochondria and pondered putting soldiers on the Atkins diet. In 2006, Darpa launched an ambitious Restorative Injury Repair program, that aims to “fully repair” body parts damaged by traumatic injury.

Earlier this year, researchers funded by that program generated new human muscle that could replace damaged tissue. Now Darpa’s asking for a device that can use adult stem cells for a regenerative free-for-all, pumping out whatever needed to repair injured body parts, including nerves, bone and skin. Already, research has proven that adult stem cells can act the same way embryonic ones do - differentiating into the highly-specified cells that form complex body parts.

According to Darpa’s solicitation, 85 percent of recent wartime injuries involved damage to the extremities and facial regions. That often means multiple surgeries, rehab and permanent disability for vets. They’re hoping to eliminate the injuries, and their long-term consequences, with a system that can reproduce in vitro tissues with the same structural and mechanical properties of the real stuff. And maybe make better versions: Darpa wants implanted results that will “replace, restore or improve tissue/organ function.”

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Scientists collaborating with each other in virtual worlds

>> Wednesday, August 05, 2009

Editor's Note: Technological advances that affect our everyday lives are often given to us by either the military or science. Which will be the driving force behind full-immersion virtual reality? This article kind of gives the edge to science.

PhysOrg.com - August 4, 2009, by Lisa Zyga

MICA members attending a regular weekly astrophysics seminar, in this case by Dr. M. Trenti, given in the StellaNova sim in Second Life. Image courtesy of Meta Institute for Computational Astrophysics (MICA).

Normally, virtual worlds are the setting of many online games and entertainment applications, but now they’re becoming a place for scientific collaboration and outreach, as well. A team of scientists from the California Institute of Technology, Princeton, Drexel University, and the Massachusetts Institute of Technology have formed the first professional scientific organization based entirely in virtual worlds. Called the Meta Institute for Computational Astrophysics (MICA), the organization conducts professional seminars and popular lectures, among other events, for its growing membership.

As MICA’s founders explain in a recent published paper, MICA is currently based in Second Life where participants use avatars to explore and interact with their surroundings, and will expand to other virtual worlds when appropriate. As of this past March, MICA had about 40 professional members and 100 members of the general public interested in learning about science, specifically astronomy. MICA is also establishing collaborative partnerships with the IT industry, including Microsoft and IBM, and plans to further develop industrial partnerships.

“Virtual worlds are already a very fruitful arena for research in social sciences and humanities, including sociology, economics, psychology, etc.,” lead author George Djorgovski told PhysOrg.com. “They are already a superb educational and outreach platform, and should be used much more. We are trying to find out what else we can do with these technologies in the natural sciences, such as physics and astronomy.”

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Sliding past the blood-brain barrier

>> Tuesday, August 04, 2009

Editor's Note: As the term implies, the blood-brain barrier is a means by which evolution has successfully protected the brain from certain types of pathogens that may be circulating in the bloodstream. Getting therapeutic objects past this barrier has been an ongoing subject of medical research for some time. This article outlines the successful passage of nanoparticles through this barrier. The therapeutic potential of this feat is hard to fathom.

PhysOrg.com - August 3, 2009

Brain cancer is among the deadliest of cancers. It's also one of the hardest to treat. Imaging results are often imprecise because brain cancers are extremely invasive. Surgeons must saw through the skull and safely remove as much of the tumor as they can. Then doctors use radiation or chemotherapy to destroy cancerous cells in the surrounding tissue.

Researchers at the University of Washington have been able to illuminate brain tumors by injecting fluorescent nanoparticles into the bloodstream that safely cross the blood-brain barrier - an almost impenetrable barrier that protects the brain from infection. The nanoparticles remained in mouse tumors for up to five days and did not show any evidence of damaging the blood-brain barrier, according to results published this week in the journal Cancer Research.

Results showed the nanoparticles improved the contrast in both MRI and optical imaging, which is used during surgery.

"Brain cancers are very invasive, different from the other cancers. They will invade the surrounding tissue and there is no clear boundary between the tumor tissue and the normal brain tissue," said lead author Miqin Zhang, a UW professor of materials science and engineering.

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Presto Change-o - Making any cell become any other cell

>> Monday, August 03, 2009

Editor's Note: A brave new world is opening up, where scientists can program cells to become other kinds of cells, hence turning skin cells into stem cells and making entire mice. This article concerns the transformation of blood cells into vision cells.

Science Daily - August 3, 2009

University of Florida researchers were able to program bone marrow stem cells to repair damaged retinas in mice, suggesting a potential treatment for one of the most common causes of vision loss in older people.

The success in repairing a damaged layer of retinal cells in mice implies that blood stem cells taken from bone marrow can be programmed to restore a variety of cells and tissues, including ones involved in cardiovascular disorders such as atherosclerosis and coronary artery disease.

"To our knowledge, this is the first report using targeted gene manipulation to specifically program an adult stem cell to become a new cell type," said Maria B. Grant, M.D., a professor of pharmacology and therapeutics at UF's College of Medicine. "Although we used genes, we also suggest you can do the same thing with drugs — but ultimately you would not give the drugs to the patient, you would give the drugs to their cells. Take the cells out, activate certain chemical pathways, and put the cells back into the patient."

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What comes after genes and memes?

>> Sunday, August 02, 2009

Editor's Note: Biological evolution uses the replication and selection of genes to propagate. Cultural evolution uses memes to do the same thing. Memes are ideas, born of intelligence, and replicated and selected by human beings. Another replicator has emerged, one without a name, but just as real nonetheless. This article points out the power of rapidly expanding binary information used by computers and servers and explores what it could mean for the human species.

New Scientist - July 31, 2009, by Susan Blackmore

WE HUMANS have let loose something extraordinary on our planet - a third replicator - the consequences of which are unpredictable and possibly dangerous.

What do I mean by "third replicator"? The first replicator was the gene - the basis of biological evolution. The second was memes - the basis of cultural evolution. I believe that what we are now seeing, in a vast technological explosion, is the birth of a third evolutionary process. We are Earth's Pandoran species, yet we are blissfully oblivious to what we have let out of the box.

This might sound apocalyptic, but it is how the world looks when we realise that Darwin's principle of evolution by natural selection need not apply just to biology. Given some kind of copying machinery that makes lots of slightly different copies of the same information, and given that only a few of those copies survive to be copied again, an evolutionary process must occur and design will appear out of destruction. You might call it "design by death" since clever designs thrive because of the many failures that don't.

The information that is copied, varied and selected is called the replicator, and the process is well understood when applied to biology. Genes are copied, mutated and selected over and over again. Assemblages of genes are used to build vehicles that carry them around, protect them and propagate them. These vehicles - the lumbering robots, as Richard Dawkins calls them - are animals and plants, the prolific and exquisitely designed products of the first replicator.

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